January 11, 2026

Beyond THC Percentage: The Role of Terpenes and the “Entourage Effect” in Medical Efficacy

When evaluating medical cannabis flowers, many patients and clinicians focus solely on the THC percentage. However, modern cannabis science suggests that therapeutic outcomes are driven by a more complex interaction known as the “Entourage Effect.”

What is the Entourage Effect?

This theory posits that cannabinoids (like THC and CBD) and terpenes (the aromatic oils in the plant) work synergistically. Together, they may enhance therapeutic benefits and modulate potential side effects better than isolated THC alone.

Key Terpenes in Medical Cultivars

At 300 Genetics, we select genetics based on comprehensive terpene profiles, not just potency.

  • Myrcene: Often associated with sedative and muscle-relaxant properties, potentially aiding sleep protocols.
  • Limonene: Studied for potential mood-elevating and anti-anxiety properties.

Caryophyllene: Unique because it interacts directly with endocannabinoid receptors, showing potential anti-inflammatory benefits.
A 25% THC flower lacking a robust terpene profile may be less clinically effective than a 20% flower with a rich, synergistic terpene content. We encourage our partner clinics to consider the full spectrum of the plant.

⚖️ Important Legal & Medical Disclaimer (Thailand 2026)

Informational Purpose Only: The content provided on this website (300genetics.com) is for educational and informational purposes only. It does not constitute professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified physician or licensed Thai Traditional Medicine (TTM) practitioner regarding any medical condition or before starting any cannabis-related therapy.

Thai Regulatory Compliance: In Thailand, cannabis is regulated for medical and holistic health use under supervision. Public recreational consumption is illegal and subject to penalties under the Public Health Act. It is the sole responsibility of the user to understand and comply with all current local laws and regulations.

Liability: This information is intended for individuals over the age of 20. 300 Genetics assumes no responsibility or liability for any misuse of the information provided herein or for any legal consequences resulting from the user's actions.

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